The toehold-switch is inactive as the Ribosome Binding Site (RBS) is hidden in a strong stem.
Upon binding of kanamycin, the regulatory construct that is fused to the aptamer and that keeps the toehold-switch in its inactive conformation (by not allowing base pairing between the regulatory construct and the toehold-switch) changes secondary structure.
If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware.
If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices.
Furthermore we discussed ways to implement new aptamers in their existing system.